Efficacy of Melaleuca alternifolia and Rosmarinus officinalis, Manuka honey-based gel, and propolis against canine Staphylococcus pseudintermedius  

Antimicrobial resistance remains one of the most crucial challenges to be solved in both human and veterinary medicine. Essential oils and honeybee products are natural compounds that are frequently used for their medicinal properties. Researchers evaluatde the antibacterial properties of tea tree (Melaleuca alternifolia), Rosmarinus officinalis,  manuka-based gel, and propolis against 23 strains of Staphylococcus pseudintermedius that had been isolated from canine pyoderma. 

Tea tree essential oil was able to generate larger inhibition zones compared to those of rosemary. Tea tree also showed in vitro antibacterial properties against Porphyromonas gingivalisPorphyromonas endodontalisS. aureusE. coliStreptococcus mutans, and Listeria monocytogenes. There was no statistical significances were found among the two oils in the ability to inhibit bacterial growth. Rosemary essential oil showed antimicrobial properties against L. monocytogenesE. coli, and Salmonella enterica

For the two honeybee products tested, the Manuka-based gel was found to have the lowest MIC, making this product one of the most promising natural antimicrobials. 

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In Vitro Efficacy of Essential Oils from Melaleuca Alternifolia and Rosmarinus Officinalis, Manuka Honey-based Gel, and Propolis as Antibacterial Agents Against Canine Staphylococcus Pseudintermedius Strains

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Effect of manuka honey on biofilm formation