Researchers evaluated one hundred seven cats from rehoming centers without a history of clinical signs of cardiac or systemic disease at the time of adoption.

Cats were reexamined for serial echocardiogram for a median of 5.6years. At baseline, 68/107 cats were normal, 18/107 were equivocal and 21/107 had HCM.

Nineteen cats developed HCM during the study period.

The factors at baseline associated with increased hazard of developing HCM were lower left atrial fractional shortening, higher left ventricular fractional shortening, and higher body weight. Cardiovascular events were observed in 21% of cats with HCM.

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Natural history of hypertrophic cardiomyopathy in cats from rehoming centers: The CatScan II study