A new scientific review finds relevant data from cannabis medical studies in companion animals. Nowadays, both low-THC and high-THC cannabis are used for medical uses. However, the majority of veterinary cannabis products contained low-THC. 

The endocannabinoid system (ECS) was characterized and described as a complex regulatory system that provides essential homeostasis mechanisms through the body. This system has been studied in humans and several animals, from birds to canines. It also plays an important role and is divided into three components: cannabinoid receptors (CBRs), endocannabinoids (eCBs), and enzymes responsible for the activation, transportation, and breakdown of eCBs.

 Most of the veterinary cannabis products have been clinically used for osteoarthritis and epilepsy in canines. For these patients, clinical research has suggested doses of 2 mg/k. The pain assessment scales have decreased after a few weeks of treatment with CBD oil, but there have not been reported changes in lameness.

Previous studies have shown that products with nearly little or no THC had efficacy to treat seizures, mild pain, and anxiety. Also, another study with oral and transdermal CBD reported being well-tolerated in canines. Interestingly, it has been reported that feeding might enhance CBD absorption compared to animals without feeding. Besides, other study finds that the combination of CBD dominant oil with standard anticonvulsant therapies has reduced the seizure frequency of canines. 

But, there is still a limited amount of research data regarding the safety and use of cannabis in veterinary medicine. It has been advised to veterinarians to apply their use carefully and consult their state veterinary medical board. 

For that, it's essential to properly understand each Cannabis compound's mechanism to develop a better clinical approach or treatments. 

To read more click on the link below:

Cannabis in Veterinary Medicine: A Critical Review