Extracts from mushrooms show inhibitory effects against FIV reverse transcriptase
Feline immunodeficiency virus (FIV) is known for causing AIDS-like symptoms in domestic and wild cats.
A study was conducted to determine the anti-FIV viral effects on mushrooms using fluorescence spectroscopy. Around 17 medicinal and edible mushrooms were collected and used to find the inhibitory effects against the enzyme FIV reverse transcriptase (FIV-RT).
Results showed that ethanol extracted from dried fruiting bodies of Inonotus obliquus has a higher inhibition value. Also, the hexane extract from dried mycelium of I. obliquus, ethanol, and water extracts from fresh fruit bodies of Phellinus igniarius had high values. In comparison, the ethanol extract from new fruiting bodies of Cordyceps sinensis, hexane extracts from dried mycelium of I. obliquus, ethanol extracts of Ganoderma lucidum, hexane extracts of fresh fruiting bodies of Morchella esculenta, and new fruiting bodies of C. sinensis showed moderate values.
This study reveals that extracts from three mushrooms I. obliquus, P. igniarius, C. sinensis, and M. esculenta showed potential anti-FIV effects.
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