Manuka honey against genetically diverse Staphylococcus pseudintermedius
Staphylococcus pseudintermedius is an opportunistic zoonotic pathogen that can cause infections which require prolonged and intensive treatment.
Researchers evaluated the ability of Manuka honey to inhibit strains of Staphylococcus pseudintermedius growth in an in vitro study.
The results showed that all strains of S. pseudintermedius were inhibited by ≤ 12% medical grade Manuka honey.
In addition, the susceptibility to tetracycline, penicillin, chloramphenicol, gentamicin was significantly increased when combined with honey, although sensitivity to oxacillin was decreased. Virulence activity was also significantly reduced in over half of isolates.
The study suggests that manuka honey is not only highly potent against novel multi-drug resistant S. pseudintermedius, but also acts synergistically with several antibiotics. In addition, manuka honey modulates S. pseudintermedius virulence activity.
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