Benign and malignant skin lesions in dogs
Papillomavirus (PV) mainly infects the squamous epithelium and may potentially lead to benign or even malignant cutaneous lesions.
A total of 314 tissue samples were collected from dogs were used in this study, including 212 cases of canine SCCs and 102 cases of CPs. The lesion distribution of these canine SCC cases was mainly on the oral mucosa (33%), followed by head and neck skin (22%), flank (13%), limbs (12%), nasal mucosa (9%), and other locations (11%), including perianal skin, tail, lungs, thyroid glands, and lymph nodes, as well as systemic.
The total number of confirmed canine papilloma was 102, and the lesions developed mainly on the skin (76%), followed by a small portion of lesions occurring in the oral cavity (22%), and one unique case occurring in the urinary bladder. Of the 102 canine papilloma cases, intranuclear viral inclusions were observed in only 21 (21%).
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