Evaluation of serum immunoglobulin E (IgE) response to aeroallergens in cats with airway eosinophilia
Feline eosinophilic airway disease occasionally has been described to be induced by allergens. A few studies have documented felines with this disease and the utility of allergy testing for respiratory tract diseases.
A case-control study examined the serum immunoglobulin E (IgE) response to allergens in cats affected with idiopathic eosinophilic airway disease. The residual serum samples from bronchoscopy with bronchoalveolar lavage in those cats were evaluated for IgE analysis. The study assessed the response to 48 allergens, including fungal organisms, weeds, grasses, trees, mites, and insects.
The results showed that the cats with airway eosinophilia had a higher positive response than the control group. But, the cats with positive IgE did not show a difference from the control group. Dust mite was the most common allergen in cats with airway eosinophilia disease. Two types of storage mites were the second most common allergen in cats with this disease.
The production of serum IgE was found in some cats with eosinophilic airway disease. However, the positive cats did not differ from the control cats, and more investigation is recommended to assess the affected cats with the control cats.
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