Fungal culture analysis of Microsporum canis dermatophytosis

Researchers evaluated medical records from 371 cats with confirmed Microsporum canis (MC) infection. The first negative fungal culture was indicative of MC in 335 (90.3%) cats. In this group, all cats were otherwise healthy and either had obvious lesions (n = 237) or no lesions or evidence of resolving lesions (n = 98).

In the 36 cats with an initial negative culture, one group consisted of healthy but lesional cats (n = 19) that had one negative fungal culture followed within the first 3 weeks of treatment followed by one or more positive fungal cultures.

In the second clinical group, cats were lesional but had concurrent medical problems (n = 17). These cats showed an initial good response to treatment (lesion resolution and an initial negative FC). However, this negative FC was followed by at least one strongly positive FC (>10 colony-forming units/plate) before proceeding to cure. These cats took the longest time to cure (mean 11 weeks; range 8-28 weeks).

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One vs two negative fungal cultures to confirm mycological cure in shelter cats treated for Microsporum canis dermatophytosis: a retrospective study.

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