As vets, we strive to keep our furry clients safe from harm, but a silent and deadly threat lurks closer than we might think. Babesia canis, an intraerythrocytic protozoan parasite transmitted by ticks, is causing a significant number of canine illnesses worldwide. A comprehensive systematic review and meta-analysis conducted by an international team of researchers sheds light on the global prevalence and associated risk factors of this formidable disease.