Researchers evaluated sixteen cases of Anthracycline overdoses, which occurred because of an error in chemotherapy preparation. Most of the overdoses were identified immediately after drug administration and the dogs were hospitalized and given supportive care for an average of 8 days. The adverse effects noted include neutropenia (94%), thrombocytopenia (88%), anemia (63%), diarrhea (63%), anorexia (56%), vomiting (38%), lethargy (31%), and nausea (25%). Two patients of the sixteen patients did not survive .

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Toxicity, outcome, and management of anthracycline overdoses in 16 dogs