Potential drugs for treatment of feline hepatic lipidosis

Researchers evaluated drugs that could be helpful to treat hepatic lipidosis in cats using  feline hepatic organoids from six cats. In the study, eight drugs were tested, of those, two were most promising and studying further.

The drug T863 inhibits DGAT1, indicating that DGAT1 is the primary enzyme responsible for TAG synthesis from external fatty acids in cat organoids. The drug AICAR may act as a lipid-lowering compound via decreasing PLIN2 mRNA.

Read more by clicking on the link below:

Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system.

Previous
Previous

Nuclear Sclerosis in Dogs

Next
Next

West Nile virus triggers brain inflammation by inhibiting protein degradation