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Efficacy of medication on horses with smoke-induced asthma

Twelve thoroughbred polo horses with smoke‐induced mild asthma were evaluated. Horses were exposed to increased ambient particulate matter

All horses completed tests after dexamethasone (20 mg IM q24h) or saline treatment (SALINE, n = 6), and after inhaled salbutamol (1500 μg). Bronchoalveolar lavage and mucus scoring were performed on day −8 and day 20..

Horses’ mucus scores improved significantly from day −8 to 20. There was a significant increase in O2peak from day 0 to 17, representing an average increase in O2peak of 13.2%. There was no difference in V˙O2 peak between treatment groups.

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Efficacy of dexamethasone, salbutamol, and reduced respirable particulate concentration on aerobic capacity in horses with smoke-induced mild asthma.