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Diagnostic value of cerebrospinal fluid analysis

Researchers evaluated the medical records of 200 dogs that  presented with epileptic seizures (ES) and also had normal neurological examination, normal complete blood count and biochemistry analysis, unremarkable MRI of the brain.

The CSF was abnormal in 30 dogs with a median total nucleated cell count of two cells/µl and median protein concentration of 0.37 g/l. Pleocytosis was recorded in 14/30 dogs and the CSF protein was increased in 22/30.

Results showed no correlation between abnormal CSF and the type or number of seizures or the time interval between the last seizure and CSF collection.

The prevalence of having a diagnosis other than suspected idiopathic epilepsy (IE) was 0.5 per cent.

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Diagnostic value of cerebrospinal fluid analysis in a population of dogs with suspected idiopathic epilepsy.