Fifty-one client-owned male cats with feline idiopathic cystitis (FIC) were evaluated by researchers. After being discharge post inital treatment, 24 cats were treated for with phenoxybenzamine and alprazolam, and with low-dose meloxicam (0.025 mg/kg/day PO) and 27 cats were treated with phenoxybenzamine and alprazolam only.

Twelve (24%) cats experienced signs of recurrent FIC within 6 months. No difference in the cumulative incidence of UO within 6 months was detected with addition of meloxicam. All cats were alive at 6 months.

Study suggests that there is little clinical benefit with the addition of low-dose meloxicam to phenoxybenzamine and alprazolam treatment for 2 weeks after discharge.

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A prospective randomized study of efficacy of 2 treatment protocols in preventing recurrence of clinical signs in 51 male cats with obstructive idiopathic cystitis.