Use of gentamicin to treat equine recurrent uveitis

A retrospective study evaluated the efficacy of intravitreal gentamicin (6 mg in 0.3 mL solution) injection in 71 horses with equine recurrent uveitis between 2010 and 2016. Aqueous flare and hyalitis were scored at the baseline in all horses, then at 15, 30, 60, 90, 180, 365, and 730 days. Forty-two animals had a score of inflammation of zero at the last examination. Among the 29 remaining horses, four did not complete the study.  Of the 25 remaining, individual inflammation scores improved in 21 cases.  Ocular hypotension, lens opacities, and retinal folds were observed, respectively, in 92%, 78%, and 28% of the 71 eyes at the baseline, and in 80%, 90%, and 36% of the 11 eyes re-evaluated at 2 years. Seventy of the horses did not develop a new observable episode of inflammation and did not require ocular medication.

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Use of Intravitreal Injection of Gentamicin in 71 Horses with Equine Recurrent Uveitis.