Frequency of Genetic Diseases in Dogs
A study examined over 83,000 mixed breed and 18,000 purebred dogs representing 330 breeds for 152 known variants. The most prevalent, and rare, disease susceptibility variants were identified across the general dog population. Approximately two in five dogs carried at least one copy of a tested disease variant. Most disease variants are shared by both mixed breeds and purebreds, while breed- or line-specificity of others is strongly suggested. Mixed breed dogs were more likely to carry a common recessive disease, whereas purebreds were more likely to be genetically affected with one. The study found genetic presence of 22 disease variants in at least one additional breed in which they were previously undescribed.
The disease prevalence information we generated during this study is available online as a free tool for breed and kennel clubs, breeders, as well as the veterinary and scientific community
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